Reproduction Abstracts

Introduction: Supplementation of appropriate amount of vitamin C (VC) improves oocyte fertilization and subsequent embryo development while high concentrations of VC rather reduce the developmental potency. To clarify the role of VC, oocytes were collected from aldehyde reductase (AKR1A) knockout mice that are unable to synthesize VC and subjected to analyses from view point of developmental potency and gene expression involved in VC metabolism.Materials...